Abstract Cancer is considered the leading cause of death worldwide, and the number of new cases is expected to rise over the next few years. In this context, plant materials are increasingly studied in the search for substances to prevent and/or treat this disease. In this work, the cytotoxic activity of extracts from plants and friable calluses of five Brazilian peanut cultivars (IAC 886, IAC Caiapó, IAC Tatu ST, IAC 8112 and BR-1) against a leukemic cell line (K562) was compared. Inhibition of K562 cells viability (79.8%) was significantly higher in response to extracts from calluses of cultivar IAC 886 as compared to extracts of aerial parts of in vivo and in vitro plants from the same cultivar. Callus extracts displayed low toxicity on non-tumor cells (NIH-3T3 fibroblasts and peripheral blood mononuclear cells). Trans-resveratrol was found in extracts from aerial parts of cultivar IAC Tatu ST and from calluses of cultivar IAC 886. In addition, three compounds with UV spectrum compatible with phenolic compounds were detected in the samples. Calluses from cultivar IAC 886 displayed higher relative contents of these compounds, which can be contributing to their cytotoxic activity.

Aim This study determined whether COVID-19 fear is correlated with sociodemographic characteristics, general health, mental health, and sleep quality in an elderly Brazilians. Methods Elderly people aged ≥ 60 years replied to an online survey containing questions about their sociodemographic characteristics; general health; levels of stress, anxiety, and depression; sleep quality; and COVID fear. Results Data were statistically analyzed using descriptive statistics (α = 5%). In total, 705 elderly people with mean age of 66 ± 5 years, and most (82.7%) respondents were women, graduated and from southeastern Brazil. COVID-19 fear correlated positively and moderately with sleep quality and symptoms of depression, anxiety, and stress (all p < 0.001). It was associated with females. Elderly people from northern and northeastern Brazil and diabetics had increased COVID-19 fear (all p < 0.05). Conclusion The fear of COVID-19 exists among Brazilian female old people, diabetics, increases anxiety and stress symptoms, and worsen sleep quality in elderly people.

Abstract: This paper aims to reflect upon Criminal Politics in regard to neoliberalism, as in Critical Criminology’s marxist-inspired norms, composing a brief analysis on the Brazilian reality. It is a theoretical literature review study, which weaves analysis on Brazil’s neoliberal agenda model and, subsequently, quests to comprehend by which means the Criminal Politics takes on as the centrepiece in this agenda, acknowledging the demand for social control through the disciplining of the labouring class and the penalisation of poverty as rebuttal to social exclusion and inequality.

Resumen: Este artículo pretende reflexionar sobre la Política Criminal en el contexto del Neoliberalismo, a partir de los preceptos de la Criminología Crítica de inspiración marxista, haciendo un breve análisis de la realidad brasileña. Se trata de un estudio teórico de revisión bibliográfica, que analiza la configuración de la agenda neoliberal en Brasil y luego busca entender cómo la Política Criminal asume la centralidad en esta agenda, respondiendo a la demanda de control social a partir del disciplinamiento de la clase trabajadora y la penalización de la pobreza como respuesta a la desigualdad y la exclusión social.

Resumo: Este artigo tem como objetivo refletir sobre a Política Criminal no contexto do Neoliberalismo, a partir dos preceitos da Criminologia Crítica de inspiração marxista, realizando uma breve análise sobre a realidade brasileira. Trata-se de um estudo teórico de revisão bibliográfica, que tece análises sobre a configuração da agenda neoliberal no Brasil e, em seguida, busca compreender de que maneira a Política Criminal assume centralidade nesta agenda, respondendo à demanda de controle social a partir do disciplinamento da classe trabalhadora e da penalização da pobreza como resposta à desigualdade e à exclusão social.

Aim This study aimed to evaluate the effect of frozen storage on the physical properties of a silicone-based test food material, highly used to evaluate the masticatory performance in research settings. Methods A total of 1,666 silicone cubes of Optosil Comfort® with 5.6-mm edges were shaped and stored at -18°C. The cubes were subsequently tested for flexural strength (maximum force, displacement, stress, and strain) before breaking (n = 136), changes in weight and size (n = 170), and masticatory performance (n = 1360) at eight timepoints: immediately after cube preparation (baseline, no freezing), and 1, 2, 3 and 4 weeks, and 2, 4 and 6 months after frozen storage. The cubes were thawed 8 h before each assessment. Results The maximum force, stress, maximum displacement, and deformation values for the cubes were not affected by freezing (P > 0.05). At all of the time points, the cubes exhibited similar weight (P = 0.366) and size (identical values). The masticatory performance for the cubes also showed no differences from baseline through 6 months (P = 0.061). Conclusion Freezing Optosil Comfort® silicone cubes did not alter the physical and mechanical properties of the material, being suitable to optimize the assessment of masticatory parameters for research purposes.

Aim This cross-sectional observational study aimed to evaluate the influence of the Universities lockdown measures on academic perspectives and psychosocial aspects of Brazilian final-year dental students. Methods 268 undergraduate students regularly enrolled in a Dentistry course at public universities were asked about anxiety, depression, stress sensitivity, and their academic perspectives by using an online survey. The Hospital Anxiety and Depression Scale (HADS) was used to measure anxiety and depression, while the Perceived Stress Scale (PSS) evaluated stress levels. The academic perspective was evaluated by five affirmatives regarding possible difficulties that will be faced when school reopens and after graduation. The possible association between fear of having COVID-19 with psychosocial outcomes and COVID-19 association with academic perspectives were analyzed by ANOVA and chi-square tests, respectively, considering a significance level of 5%. Results Considering possible associations between the fear of having COVID-19 and psychosocial aspects, significant values were found for anxiety (P = 0.018) and stress sensitivity (P = 0.002). Regarding students’ academic perspectives, COVID-19 had significant impact on less opportunity to perform procedures (P = 0.023), additional expenses with personal protective equipment (P = 0.007), and concerns of consulting elderly people (P = 0.012). Conclusion The COVID-19 pandemic led to increased psychological impairments and enlarged concerns with learning and biosecurity, which might impact academic perspectives. Thus, being aware of these apprehensions, university professors and staff can improve the clinical training of final-year dental students in an empathetic way.

Abstract This study aimed to evaluate the correlation between two Oral Health-Related Quality of Life (OHRQoL) questionnaires (the Oral Health Impact Profile (OHIP-14) and the Geriatric Oral Health Assessment Index (GOHAI)) and to investigate the factors associated with the OHRQoL of institutionalized elderly individuals. A cross-sectional multicenter study was performed with 344 institutionalized elderly individuals residing in two Brazilian cities. Six trained researchers interviewed the elderly individuals. Sociodemographic data were collected from medical records. Dental caries experience and the use of and need for dentures were recorded through oral examination performed by two trained examiners. A Likert scale (1–5 points) was used to assess general health and self-perceived oral health. The number of chewing cycles needed to chew a portion of peanuts was used to assess the swallowing threshold. The OHIP-14 and GOHAI were used to evaluate OHRQoL, and statistically significant correlations were assessed using Spearman’s correlation test (p < 0.05). Poisson regression (p < 0.05) was used to investigate the association of OHRQoL with independent variables. Scores on the OHIP-14 (7.57 ± 8.63) and GOHAI (32.46 ± 3.85) were strongly and inversely correlated (r2 = -0.671, p < 0.001), although these measures were associated with different factors. A higher OHIP-14 total score (worse OHRQoL) was associated with female gender, a greater number of healthy teeth, worse self-perceived general health and oral health, and a lower swallowing threshold (p < 0.05). A higher GOHAI total score (better OHRQoL) was associated with a greater number of filled teeth, better self-perceived oral health and a greater swallowing threshold (p < 0.05). In conclusion, worse OHRQoL among institutionalized elderly individuals is associated with worse self-perceived oral health and a greater swallowing threshold.

ABSTRACT Objective: To evaluate the influence of tooth loss and the use of removable dentures on chewing function and nutritional status of institutionalized elders. Material and Methods: Cross-sectional study with 155 elders from seven long-stay institutions in João Pessoa, Brazil. The participants were classified according to the presence of reminiscent teeth and use of dentures in four levels: toothless, without denture (1); toothless with a complete denture (2); partial toothless without denture (3) and partial toothless with a partial denture (4). Nutritional status was assessed using the Mini-Nutritional Assessment (MNA) instrument and the Body Mass Index (BMI). Swallowing threshold was used for the assessment of masticatory function, using a portion of roasted peanuts (3.7 g). Comparisons among groups were performed using Kruskal-Wallis test with Bonferroni adjustment, considering p<0.05. Results: MNA (p=0.702) and BMI (p=0.884) were not modified in relation to the presence of teeth and denture use. Toothless individuals without dentures had a lower swallowing threshold (p<0.001), whilst partial toothless with dentures had better masticatory function (p>0.05). Conclusion: The presence of reminiscent teeth and the use of dentures do not influence the nutritional status of the elders but interfere with the masticatory function. Prosthetic rehabilitation is desirable for complete toothless individuals.

Abstract BoNT-A has been widely used for TMD therapy. However, the potential benefits compared to dry needling techniques are not clear. Objective this study aimed to compare the immediate effects of botulinum toxin type A (BoNT-A) injections and Acupuncture in myofascial temporomandibular disorders (TMD) patients. Methodology 54 women were divided into three groups (n=18). AC patients received four sessions of traditional acupuncture, being one session/week during 20-min. BoNT-A patients were bilaterally injected with 30U and 10U in masseter and anterior temporal muscles, respectively. Moreover, a control group received saline solution (SS) in the same muscles. Self-perceived pain was assessed by visual analog scale, while pressure pain threshold (PPT) was verified by a digital algometer. Electromyographic evaluations (EMG) of anterior temporal and masseter muscles were also measured. All variables were assessed before and 1-month after therapies. The mixed-design two-way repeated measures ANOVA and Tukey’s post-hoc tests were used for analysis, considering a=0.05. Results Self-perceived pain decreased in all groups after one month of therapy (P<.001). BoNT-A was not better than AC in pain reduction (P=0.05), but both therapies were more effective in reducing pain than SS (P<0.05). BoNT-A was the only treatment able to improve PPT values (P<0.05); however, a severe decrease of EMG activity was also found in this group, which is considered an adverse effect. Conclusion after one month of follow-up, all therapies reduced the self-perceived pain in myofascial TMD patients, but only BoNT-A enhanced PPT yet decreased EMG.

ABSTRACT Many factors may influence the genetic stability of plant in vitro clones, among which the genotype and the regenerative process induced by plant growth regulators. The resulting somaclonal variations may be useful for breeding projects, but may be detrimental to germplasm conservation. The objective of this work was to evaluate the genetic stability of Solanum melongena cv. ‘Florida Market’ clones, obtained in response to different plant growth regulators. For the production of clones, leaf explants were used from commercial seed germinated plants. The explants were inoculated in Murashige and Skoog medium supplemented with different plant growth regulators at predefined concentrations. The DNA was extracted by the CTAB method from leaves of complete plants obtained by somatic embryogenesis induced by naphthaleneacetic acid (NAA) or indirect organogenesis induced by benzylaminopurine (BAP) or thidiazuron (TDZ). For the RAPD, 117 DNA samples were amplified by ten decamer primers and 49 specific bands were selected among the products for the comparative study. A total of 5733 fragments were obtained, with a rate of 5.37% polymorphism. NAA did not generate polymorphism and the BAP was responsible for the highest rate obtained (14.28%). Two RAPD primers were identified as markers for monitoring the genetic stability of eggplant. The polymorphic pattern was observed only in clones originating from indirect organogenesis. These results indicate the usefulness of a monitoring protocol for studies using in vitro cloned eggplant.

RESUMEN Muchos factores pueden influir en la estabilidad genética de los clones de plantas in vitro, entre los que se encuentran el genotipo y el proceso regenerativo inducido por los reguladores del crecimiento. Por lo tanto, las variaciones somaclonales resultantes del cultivo pueden ser útiles para proyectos de mejoramiento genético, pero pueden ser perjudiciales para la conservación de germoplasma. El objetivo de este estudio fue evaluar la estabilidad genética de Solanum melongena cv. ‘Florida Market’, obtenida en respuesta a diferentes reguladores del crecimiento. Para la producción de clones se utilizaron explantes de hojas provenientes de plantas obtenidas de semillas germinadas. Los explantes se inocularon en medio de cultivo Murashige y Skoog con los diferentes reguladores del crecimiento en concentraciones predefinidas. El ADN se extrajo mediante el método CTAB a partir de plantas completas obtenidas por medio de embriogénesis somática inducida por ácido naftalenoacético (ANA) u organogénesis indirecta inducida por bencilaminopurina (BAP) o tidiazurón (TDZ). Para el RAPD, 117 muestras de ADN se amplificaron mediante diez cebadores y se seleccionaron 49 bandas puntuales entre los productos, para el estudio comparativo. Se obtuvieron un total de 5733 fragmentos, con una tasa de 5.37% de polimorfismo. ANA no generó polimorfismo y BAP fue responsable de la tasa más alta obtenida (14.28%). Se identificaron dos cebadores RAPD como marcadores para monitorear la estabilidad genética de la berenjena. El patrón polimórfico se observó solo en los clones originados en la organogénesis indirecta. Estos resultados indican la utilidad de un protocolo de monitoreo para estudios que usan berenjena clonada in vitro.

Resumo A utilização de overdentures suportadas por dois implantes melhora a mastigação de pacientes idosos edêntulos que apresentam rebordos residuais reabsorvidos. No entanto, pouco se sabe sobre os efeitos de overdentures suportadas por único implante central mandibular (SIO) em relação à percepção oral e função mastigatória em tais idosos. O atual estudo comparou os efeitos de próteses totais convencionais (CD) e SIO na capacidade de sensorimotora oral (OSA), função mastigatória e ingestão nutricional de idosos com altura de rebordos mandibulares tipo III e IV de acordo com a Colégio Americano de Prótese. Doze idosos receberam primeiramente novas CD convencionais, as quais, posteriormente, foram transformadas em SIO. Variáveis foram avaliadas após o uso de cada prótese durante 2 meses. Para avaliar OSA, os idosos fecharam os olhos e testaram oralmente a identificação de formatos geométricos confeccionados de cenouras cruas. Um dispositivo cinesiográfico foi utilizado para medir os movimentos durante a mastigação de material de teste (Optocal). A performance mastigatória (MP) foi determinada com o método de fracionamento de peneiras e um diário de alimentação aplicado por 3 dias consecutivos verificou a ingestão de nutrientes com base em uma Tabela Brasileira Padrão de Composição de Alimentos. Os dados foram analisados utilizando os testes Wilcoxon signed rank test e Student’s paired t test (p<0,05). OSA resultados não diferiram de acordo com o tipo de prótese. No entanto, as velocidades de abertura e fechamento durante a mastigação e MP aumentaram após a inserção de SIO (p<0,05). Embora não tenha sido observada diferença na ingestão da maioria dos nutrientes, a ingestão de sódio diminuiu após a inserção de SIO (p<0,05). O uso de SIO não teve efeito sobre OSA, mas melhorou significativamente a mastigação e a ingestão de sódio de idosos com altura de rebordos residuais reduzidas (Registro Brasileiro de Ensaios Clínicos # RBR-3kgttj).

Abstract The use of two-implant overdentures improves mastication of edentulous elderly patients. However, little is known about the effects of single-implant overdentures (SIO) on oral perception and masticatory function in such elders. This study compared the effects of conventional complete dentures (CD) and SIO on the oral sensorimotor ability (OSA), masticatory function, and nutritional intake of elderly people with residual alveolar mandibular height classified as Class III or IV according to the American College of Prosthodontics. Twelve elders first received new conventional CD, which were later converted to SIO. All variables were evaluated after use of each prosthesis for 2 months. To evaluate OSA, elders closed their eyes and orally identified test pieces prepared from raw carrots. A kinesiographic device was used to measure chewing movements during mastication of a test material (Optocal). Masticatory performance (MP) was determined with the sieving method, and a 3-day food diary verified nutrient intake based on a standard Brazilian Food Composition Table. Data were analyzed using the Wilcoxon signed rank test and Student’s paired t test (P < 0.05). OSA results did not differ according to prosthesis type. However, opening and closing velocities during chewing and MP increased after SIO insertion (P < 0.05). Although no difference was observed in the intake of most nutrients, sodium ingestion decreased after SIO insertion (P < 0.05). SIO use had no effect on OSA, but significantly improved mastication and sodium intake of elders with decreased residual ridges height (Brazilian Registry of Clinical Trials #RBR-3kgttj).

Abstract Passiflora species are well known for their common use in popular medicine for the treatment of several diseases, such as insomnia, anxiety, and hysteria, in addition to their anti-inflammatory, antioxidant, analgesic and antibacterial potential. However, few data about the chemical composition and the medicinal potential of in vitro derived materials are available. Therefore, the goal of this work was to compare, for the first time, the phytoconstituents of in vitro derived materials of four Passiflora species, and evaluate the antibacterial potential of their extracts against 20 Gram-positive and negative strains. Chromatographic analysis indicated the presence of saponins in roots extracts from all studied species, whereas leaf extracts presented both saponins and flavonoids. Extracts from leaves and roots of P. alata and P. foetida exhibited a selective inhibitory activity against B. thuringiensis and S. pyogenes, which might be related to the presence of a high concentration of secondary metabolites, including flavonoids and saponins.

Resumo A morfologia craniofacial afeta a performance mastigatória em individuos dentados saudáveis, mas pouco é conhecido sobre seus efeitos em pacientes com desordens temporomandibulares (DTMs) com sintomatologia dolorosa. Quarenta e oito pacientes do gênero feminino (idade média de 28±5,8 anos) com DTM e sintomatologia dolorosa foram submetidas à radiografia cefalométrica lateral. Por meio da análise cefalométrica de Ricketts e método Vert, as voluntárias foram divididas segundo a morfologia crabiofacial em: braquifaciais (n=22), mesofaciais (n=13) ou dolicofaciais (n=13). O Research Diagnostic Criteria for TMD (RDC/TMD) foi utilizado para diagnosticar a presença de DTM em cada paciente. A intensidade de dor foi reportada por cada paciente usando a escala visual analógica (EVA). A força máxima de mordida (FMM) foi medida com sensores de pressão colocados na região de primeiros molares. A performance mastigatória (PM) foi avaliada por meio da mastigação de material artificial confeccionado à base de silicone e determinada pelo tamanho da partícula, usando o método de fracionamento em peneiras. A habilidade mastigatória (HM) foi avaliada por meio de sete tipos de alimento e analisada por meio de EVA. Os dados foram analisados por ANOVA, seguido por teste de Tukey-Kramer (p<0,05). A FMM foi diferente entre cada grupo, sendo que as pacientes braquifaciais apresentaram os maiores valores. Não houve diferença na PM entre os grupos. Os grupos somente diferiram quanto à HM para mastigar apenas um dos sete tipos de alimentos avaliados. Em resumo, a morfologia craniofacial afeta a FMM sem prejudicar a PM ou HM em pacientes com DTM e sintomatologia dolorosa.

Abstract Craniofacial morphology affects masticatory performance in healthy dentate subjects, but little is known about its effects in patients with painful temporomandibular disorders (TMDs). Forty-eight female patients (mean age of 28±5.8 years) with painful TMDs underwent lateral cephalometric radiography. Using Ricketts' cephalometric analysis and the Vert method, subjects were assigned to three groups according to their craniofacial morphology: brachyfacial (n=22), mesofacial (n=13), and dolichofacial (n=13). Research diagnostic criteria for TMD were used to confirm the TMD diagnosis for each patient. Pain intensity was reported by each patient based on a visual analog scale (VAS). Maximum bite force (MBF) was measured with pressure sensors placed on the first molar site. Masticatory performance (MP) was assessed by chewing a silicone-based artificial material and determining the resulting particle size by the sieve method. Chewing ability (CA) was evaluated for seven food types and analyzed by a VAS questionnaire. Data were analyzed by one-way ANOVA followed by a Tukey-Kramer test (p<0.05). MBF differed in each group, with brachyfacial patients having the highest MBF values. There was no difference in MP among the groups. The groups differed only in their ability to chew one of the seven evaluated food types. In summary, craniofacial morphology affects the MBF without impairing MP or CA in patients with painful TMDs.

Resumo Este estudo teve como objetivo avaliar objetiva e subjetivamente a saúde bucal em idosos com doença de Parkinson (DP), usando avaliações clínicas bucais e do General Oral Health Assessment Index (GOHAI). Os participantes foram 37 indivíduos usuários de prótese removível, 17 com DP (idade média 69,59±5,09 anos) e 20 sem DP (idade média 72,00±5,69 anos). A avaliação objetiva incluiu avaliação de características bucais,incluindo número de dentes remanescentes; dentes cariados, perdidos e obturados (CPOD); índice de placa visível (IPV), a taxa de fluxo salivar e as condições das próteses removíveis. A avaliação subjetiva incluiu autopercepção da saúde bucal, coletada usando o índice GOHAI. O número de dentes remanescentes, CPOD, IPV, fluxo salivar e os dados GOHAI foram comparadas entre os grupos utilizando o teste t . As condições das próteses removíveis foram analisadas utilizando o teste χ2 (p<0,05). Não houve diferenças entre os grupos no número de dentes remanescentes, CPOD, IPV ou fluxo salivar (p>0,05). Maiores defeitos na prótese superior foi observada no grupo controle (p=0,037). As pontuações do GOHAI foram baixa para o grupo DP e moderada para os controles, com diferença entre os grupos (p=0,04). Como conclusão, os idosos com doença de Parkinson tem saúde bucal semelhante aos controles. Embora todos os idosos tenham poucos dentes remanescentes, alto CPOD e alto IPV, os idosos com DP apresentaram autopercepção mais negativa da sua saúde bucal em relação aos controles.

Abstract This study aimed to evaluate objectively and subjectively the oral health of elders with Parkinson's disease (PD), using clinical oral assessments and the General Oral Health Assessment Index (GOHAI). Subjects included 37 removable prosthesis wearers, 17 with PD (mean age 69.59±5.09 years) and 20 without PD (mean age 72.00±5.69 years). The objective assessment included an evaluation of oral characteristics, including the number of remaining teeth, decayed, missing and filled teeth (DMFT), visible plaque index (VPI), salivary flow rate and removable prosthesis conditions. The subjective assessment included self-perception of oral health collected using the GOHAI index. The number of remaining teeth, DMFT, VPI, salivary flow rate and GOHAI data were compared between the groups using t-tests. Removable prosthesis conditions were analyzed using χ2 tests (p<0.05). There were no group differences in the number of remaining teeth, DMFT, VPI or salivary flow rate (p>0.05). Greater maxillary prosthesis defects were observed in the control group (p=0.037). GOHAI scores were low for the PD group and moderate for controls, yielding a group difference (p=0.04). In conclusion, elders with PD have similar oral health to controls. Although all elders had few remaining teeth, high DMFT and high VPI, PD elders had more negative self-perceptions of their oral health than did the controls.

Resumo Objetivou-se com este trabalho estimar a qualidade da massa de forragem de uma pastagem nativa com 70% de cobertura de capim-annoni (Eragrostis plana Nees) sob pastejo contínuo de vacas primíparas. As características químicas da forragem dos componentes folha e colmo de capim-annoni e espécies nativas avaliadas foram: digestibilidade in vitro da matéria orgânica (DIVMO), proteína bruta (PB) e fibra em detergente neutro (FDN). O perfil metabólico proteico e mineral no sangue das vacas foi relacionado com os suplementos sal comum, Fosbovi pronto®, Foscromo seca® e Fosbovi reprodução®. Verificaram-se maiores teores de PB na folha e colmo de capim-annoni no inverno (9,4% e 6,7) e primavera (8,9% e 6,6), respectivamente. As variáveis metabólicas protéicas no sangue não diferiram entre suplementos (P>0,05), mas os níveis de albumina (34,5 a 25,3 g/L) e ureia (36,2 a 30,1 mg/dL) diminuíram do inverno para verão. Houve deficiência dos teores médios do mineral fósforo para vacas suplementadas com Foscromo seca® (3,9), Fosbovi pronto® (3,3) e sal comum (2,2) na primavera e sal comum no verão (2,9 mg/dL). Vacas primíparas manejadas em pastagem nativa com predominância de 70% de cobertura de capim-annoni exigem suplementação do mineral fósforo com Fosbovi reprodução® nas estações da primavera e verão.

Abstract The objective of this research was to evaluate the quality of the forage mass of a native pasture covered by 70% of Eragrostis plana Nees (South African lovegrass) under continuous grazing of primiparous cows. The following chemical characteristics of forage components leaves and stems of South African lovegrass and native species were evaluated: organic matter in vitro digestibility (OMIVD), crude protein (CP), and neutral detergent fiber (NDF). The protein and mineral metabolic profile in blood was associated with the supplements common salt, mineral salt, protein salt and reproduction salt. There was higher crude protein content in leaves and stems of South African lovegrass in winter (9.4% and 6.7) and spring (8.9% and 6.6), respectively. Metabolic protein in the blood did not differ among supplements (P> 0.05), but levels of albumin (34.5 to 25.3 g/L) and urea (36.2 to 30.1 mg/dL) decreased from winter to summer. There was deficiency of the average content of mineral phosphorus for cows supplemented with protein salt (3.9), mineral salt (3.3) and common salt (2.2) in spring and common salt (2.9 mg/ dL) in summer. Primiparous cows managed on native pasture with a prevalence of 70% coverage of South African lovegrass need mineral phosphorus supplementation with reproduction salt in spring and summer.

Resumo: Este estudo avaliou a qualidade de vida relacionada à saúde bucal (QVRSB) em indivíduos parcialmente dentados, apresentando perda extrema de dentes na região posterior com ausência de dentes pós-caninos, comparando a reabilitação por meio de próteses parciais removíveis convencionais (PPRs) e PPRs implanto-suportadas. A QVRSB foi mensurada utilizando a versão brasileira do Oral Health Impact Profile (OHIP-49). Doze indivíduos apresentando edentulismo total maxilar e Classe I de Kennedy mandibular (idade média 62,6±7,8 anos) receberam primeiramente próteses totais maxilares e PPRs mandibulares convencionais de extremidade livre. Após dois meses de uso destas próteses, a QVRSB dos voluntários foi avaliada. Implantes osseointegrados foram bilateralmente instalados na região de primeiros molares inferiores e, após quatro meses, pilares do tipo bola foram instalados para suportar a extremidade livre da PPR. Após dois meses a QVRSB dos voluntários foi reavaliada. O teste pareado de Wilcoxon foi utilizado para avaliar as diferenças de QVRSB (α=0,05). Os resultados mostraram melhora em todos os domínios do OHIP-49 (p<0,05) após a associação dos implantes à PPR. PPRs de extremidade livre mandibulares implanto-suportadas melhorou significativamente a QVRSB.

Abstract: This study aimed to evaluate oral health-related quality of life (OHRQoL) in partially dentate subjects, presenting extreme tooth loss in posterior region with missing post-canines, comparing the use of conventional removable partial dentures (RPDs) and implant-supported RPDs. OHRQoL was measured using the Brazilian version of the Oral Health Impact Profile. Twelve subjects presenting maxillary total and mandibular Kennedy Class I edentulism (mean age 62.6±7.8 years) first received complete maxillary dentures and conventional mandibular free-end RPDs. After two months, the subjects had their OHRQoL assessed. Osseointegrated implants were inserted bilaterally in the mandibular first molar regions, and after four months ball abutments were placed to support the free-end RPD. Two months later, the patients had their OHRQoL reassessed. Wilcoxon signed-rank test was used to evaluate differences in OHRQoL (α=0.05). Results showed improvement in all OHIP-49 domains (p<0.05) after associating implants to the RPD. The mandibular implant-supported free-end RPD significantly improved OHRQoL.